Mathematical Modeling in Systems Biology#
Course information#
👩🏫 Instructor: An-Chi Wei @ MD 521
🦜 Teaching assistant: Wen-Wei Tseng @ MD 705
📝 Announcements & homeworks: NTU Cool
📗 Textbook: Mathematical Modeling in Systems Biology(2013), by Brian P. Ingalls (pdf, MATLAB code)
📚 Additional materials
An Introduction to Stochastic Processes with Applications to Biology (pdf)
Course content#
Chapter 1-4 describes mathematical modelling in molecular systems biology.
Basic notions of mathematical modelling.
Dynamic mathematical models of chemical reaction networks. (ODE models)
Biochemical kinetics of enzyme-catalysed reactions and cooperative binding.
Model reductions.
Analyzing differential equation models: phase plane, stability, bifurcations, sensitivity analysis.
Chapter 5 and beyond are applications in specific biological domain(s).
Stoichiometric modelling for large-scale metabolic networks. e.g. COBRA
Signal transduction pathways.
Gene regulatory networks.
Electrophysiology and action potentials in exitable cells.
Notebook execution status#
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Run Time (s) |
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2023-10-27 12:35 |
auto |
2.96 |
✅ |
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2023-10-27 12:35 |
auto |
2.17 |
✅ |
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2023-10-27 12:35 |
auto |
3.45 |
❌ |
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2023-10-27 12:35 |
auto |
7.68 |
✅ |
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2023-10-27 12:35 |
auto |
2.1 |
✅ |
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2023-10-27 12:36 |
auto |
1.91 |
✅ |
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2023-10-27 12:36 |
auto |
13.32 |
✅ |
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2023-10-27 12:36 |
auto |
1.45 |
✅ |